About the journal
Iranian Journal of Organic Chemistry (Iran JOC) is published quarterly by the Islamic Azad University of Qaemshahr. Copyright is reserved by the Islamic Azad University of Qaemshahr.
The Iranian Journal of Organic Chemistry is an open access scientific international journal which covers fundamental research in theory and practice organic chemistry, including organic synthesis, organic reactions, natural product chemistry and structural investigations. Iran JOC is published every three month by Islamic Azad University of Qaemshahr, Qaemshahr, Islamic Republic of Iran. The journal publishes full research papers, communications and reviews in English. All enquiries to the editorial office and the support team should be written in English
Abbreviation:
Iran J. Org. Chem.
Copyright Information:
The author warrants that this research work has not been published and will not be published elsewhere prior to publication by the publisher. By submitting a typescript, the authors agree that the copyright for their paper is transferred to the publisher, if and when the paper is accepted for publication.
Recent Articles
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Open Access Article
1 - Substituent effect on the stability and electronic properties of naphthalene and azulene: A computational investigation
Reza Jafari Reza Ghiasi Bita MohtatIssue 4 , Vol. 14 , Autumn 2022In this research, substituent effect on the stability and electronic properties of naphthalene and azulene studied. Hydrogen atoms of the studied molecules were replaced with methyl, fluoride and chloride substituents. Calculations were done at the M062X/6-311G(d,p) lev MoreIn this research, substituent effect on the stability and electronic properties of naphthalene and azulene studied. Hydrogen atoms of the studied molecules were replaced with methyl, fluoride and chloride substituents. Calculations were done at the M062X/6-311G(d,p) level of theory. Bicyclobutane mechanism was considered for the rearrangement of azulene to naphthalene and substituent effect on the activation energy values were illustrated with the density functional calculations. Harmonic oscillator model of aromaticity (HOMA) parameters were used to illustration of aromoaticity in the studied molecules. Also, frontier orbital analysis in the azulenes and naphthalenes were reported. Manuscript profile -
Open Access Article
2 - Synthesis of some chiral compounds using (MWCNTs)-COOH/Fe3O4-CaO magnetic nanostructures
Omekolsoom Shabani Navabeh Nami Rahimeh Hajinasiri Masoumeh HosseinzadehIssue 1 , Vol. 15 , Winter 2022The condensation of dimedone with sugars in the presence of a catalytic amount of (MWCNTs)-COOH/Fe3O4-CaO magnetic nanostructure gave some asymmetric furan derivatives in good yields. The products were identified by FT-IR, NMR spectra, and elemental analysis.The condensation of dimedone with sugars in the presence of a catalytic amount of (MWCNTs)-COOH/Fe3O4-CaO magnetic nanostructure gave some asymmetric furan derivatives in good yields. The products were identified by FT-IR, NMR spectra, and elemental analysis. Manuscript profile -
Open Access Article
3 - Characterization of the mechanical properties of sago polymer films incorporated with the Flax seed extract, nano Zinc-oxide and nanozinc oxide-cadmium
Mohammad Mohammadi Masoumeh Hosseinzadeh Sadegh SalmanpourIssue 3 , Vol. 15 , Summer 2023Today, the tendency to use biodegradable packaging, including coatings and edible films, is increasing day by day in the industry due to the fact that they are free from synthetic chemicals and do not cause environmental pollution. In this regard, the use of combination MoreToday, the tendency to use biodegradable packaging, including coatings and edible films, is increasing day by day in the industry due to the fact that they are free from synthetic chemicals and do not cause environmental pollution. In this regard, the use of combinations of plant extracts can greatly improve the efficiency of this type of packaging. The purpose of this research is to investigate the effect of alcoholic extracted from flax seed on the mechanical properties of sago starch edible film. In the research biofilm based on sago starch incorporated with the flax seed alcoholic extract (2, 4, and 6) grams , using nano zincoxide and nano zincoxide-Cds5% its property the mechanical Tensile strength(TS) and Elongation at break (EAB) and mechanical properties were evaluated with an increase in the content of the extract. The best results for the concentration of 6gram extract mixed with 0.01gram nanoparticle zinc oxide-Cds5%. Which is the lowest tensile strength and highest elongation at break. Manuscript profile -
Open Access Article
4 - A novel three-component reactions of 4-hydroxycumarine for the synthesis of oxazine derivatives in water
Seyyed Jalal Shams Najafi Maryam Ghazvini Atefeh NavabiIssue 3 , Vol. 15 , Summer 2023A simple and proficient method for the synthesis of 1,3-benzoxazine derivatives via three-component reaction of isocyanide and isoquinoline with 2-naphthol in water in the presence of piperidine at 70oC is reported.A simple and proficient method for the synthesis of 1,3-benzoxazine derivatives via three-component reaction of isocyanide and isoquinoline with 2-naphthol in water in the presence of piperidine at 70oC is reported. Manuscript profile -
Open Access Article
5 - Cellulose nanocrystal functionalized palladium nanoparticles as an efficient heterogeneous catalyst for the synthesis of α-amino nitriles via Strecker reaction
Atieh Mirosanloo Daryoush Zareyee Mohammad KhalilzadehIssue 3 , Vol. 15 , Summer 2023An efficient route reported to the application of palladium nanoparticles dispersed on 2-aminopyrimidine functionalized cellulose nanocrystal (CNC-AMPD-Pd) as a novel, suitable and reusable catalyst in the one-pot, three component synthesis of different α-aminonit MoreAn efficient route reported to the application of palladium nanoparticles dispersed on 2-aminopyrimidine functionalized cellulose nanocrystal (CNC-AMPD-Pd) as a novel, suitable and reusable catalyst in the one-pot, three component synthesis of different α-aminonitriles at ambient temperature under solvent free reaction conditions. The heterogeneous catalyst could be easily separated from the reaction mixture and reused at least 6 times with no significant loss of catalytic activity. Manuscript profile -
Open Access Article
6 - The possibility of adsorption of Duloxetine antipsychotic drug from blood plasma by using its molecular imprinted polymer
Naghmeh Ali Kahi Bahram Daraei Leila Torkian Maryam Shekarchi AmirHossein MonzaviIssue 1 , Vol. 15 , Winter 2022This paper reveals about the use of a molecular imprinted polymer (MIP) as a suitable sorbent for solid phase extraction application of Duloxetine (DUL) drug from the human blood plasma. Reproduction of the natural receptors of DUL antipsychotic via synthesis of its MIP MoreThis paper reveals about the use of a molecular imprinted polymer (MIP) as a suitable sorbent for solid phase extraction application of Duloxetine (DUL) drug from the human blood plasma. Reproduction of the natural receptors of DUL antipsychotic via synthesis of its MIP might result in formation of specialized active sites, which make the MIP able to link with that drug. Thus, this MIP selectively absorbs the DUL molecules from the plasma due to the synthesizing the MIP in the presence of this drug. In this study, the precipitation polymerization approach was used; in which, 2,2-azobisissobutyronitrile (AIBN; as the initiator), ethylene glycol dimethacrylate (EGDMA; as the cross-linker), and methacrylic acid (MAA; as the functional monomer) were applied. In addition, the adsorption of the drug from the plasma was investigated by HPLC system. Manuscript profile -
Open Access Article
7 - Green synthesis of iminooxazoles using one-pot multicomponent reactions of isocyanates
Mohaddeseh Yahyanezhad Kordmahalleh Ali Varasteh Moradi Maziar Ahmadi Golsefidi Zinatossadat HossainiIssue 3 , Vol. 15 , Summer 2023The thiazolimide derivatives are obtained in good to excellent yields by proceeding through a simple, mild, and efficient procedure utilizing isothiocyanate, ammonium acetate and activated acetylenic compounds in the presence of triphenylphosphine in water at room tempe MoreThe thiazolimide derivatives are obtained in good to excellent yields by proceeding through a simple, mild, and efficient procedure utilizing isothiocyanate, ammonium acetate and activated acetylenic compounds in the presence of triphenylphosphine in water at room temperature. Manuscript profile -
Open Access Article
8 - An efficient synthesis of new derivatives of thiazole using multicomponent reactions
Mahboubeh Ghasemian Dazmiri Loghman MoradiIssue 3 , Vol. 15 , Summer 2023N-methyl imidazole accelerated synthesis of thiazole derivatives by employing of three-component reactions of primary amines, dialkyl acetylenedicarboxylates and isothiocyanates under solvent-free conditions at room temperature in a good yield. The above synthetic proce MoreN-methyl imidazole accelerated synthesis of thiazole derivatives by employing of three-component reactions of primary amines, dialkyl acetylenedicarboxylates and isothiocyanates under solvent-free conditions at room temperature in a good yield. The above synthetic procedure offers rapid access to novel and diversely substituted thiazole derivatives. Manuscript profile -
Open Access Article
9 - Green synthesis of morpholine-2-thione by multicomponent reaction of aziridines
Narges Ghasemi Samaneh sadat SharifiIssue 3 , Vol. 15 , Summer 2023A series of substituted morpholine-2-thione derivatives were synthesized via one-pot multicomponent reactions of nitromethane, carbon disulfide and aziridine in the presence of Et3N under solvent-free conditions. Particularly valuable features of this method include hig MoreA series of substituted morpholine-2-thione derivatives were synthesized via one-pot multicomponent reactions of nitromethane, carbon disulfide and aziridine in the presence of Et3N under solvent-free conditions. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure. Manuscript profile -
Open Access Article
10 - Characterization of the mechanical properties of the sago polymer films incorporated with the Abelmoschus esculentus extract nano Zinc-oxide and nanozincoxide-cadmium
Majedeh Mansourian, Masoumeh Hosseinzadeh* Ali MirabiIssue 3 , Vol. 15 , Summer 2023Sago starch polymer is widely used in food, pharmaceutical, textile, etc industries. Their combination with other materials such as sorbitol and glycerin increases their mechanical properties. Mechanical properties are important for edible films. Mechanical tests of the MoreSago starch polymer is widely used in food, pharmaceutical, textile, etc industries. Their combination with other materials such as sorbitol and glycerin increases their mechanical properties. Mechanical properties are important for edible films. Mechanical tests of the films were performed in accordance to the standard methods. In this regard, the use of various herbal extracts can greatly improve the efficiency of the packaging.In the research biofilm based on the sago starch incorporated with the Abelmoschus esclentus alcoholic extract (2, 4, and 6 grams) and Sorbitol/glycerol was used as a plasticizer and films were prepared under controlled conditions by the casting method using nano zinc oxide and nano zincoxide -Cds5% its properties the mechanical tensile strength (TS) and elongation at break (EAB) and mechanical properties were evaluated with a decrease in the content of the extract. The best results for the concentration of 2gram extract mixed with 0.01gram nanoparticle zinc oxide-Cds5%. Which is the lowest tensile strength and highest elongation at break. Manuscript profile